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Harris is now the leading run-scorer in the women's competition
Grace Harris once again led London Spirit to victory by steering them home in a tense chase of 123 against Manchester Originals at Old Trafford.
The defending champions, who won a final-ball thriller on Saturday and now have three wins from three this year, stuttered to 56-3 after 59 balls but Australia international Harris hit 50 not out as the Spirit edged over the line again, winning by three wickets and with two balls to spare.
Having swung the match in her side's favour with a flurry of boundaries, Harris lost the strike at the finish and Kathryn Bryce dismissed Issy Wong and Charlie Dean in consecutive deliveries.
That left nine needed from six balls but Sarah Glenn, who earlier took a tidy 1-18, edged the hat-trick ball for four and drove the winning runs to end 10 not out.
Earlier, Spirit took regular wickets throughout to limit Originals to a below-par total.
The hosts were 10-2 when New Zealand international Melie Kerr was run out for one and Spirit captain Dean halted a counter-attack of 26 from 20 balls by Originals skipper Beth Mooney.
West Indies international Deandra Dottin dragged the score up with 36 from 30 balls but she was caught hitting the final ball of the innings to deep mid-wicket.
The Originals stay fifth with one win and two defeats from their first three matches - already eight points behind Spirit who lead the way.
What is happening on Tuesday?
Birmingham Phoenix host Oval Invincibles on Tuesday. The women's game, with the Invincibles looking for their first win, begins at 15:00 BST. The men's follows at 18:30.
You will be able to watch both games lives on BBC Two and BBC iPlayer.
You can follow ball-by-ball commentary on BBC Radio 5 Sports Extra, BBC Sounds and the BBC Sport website and app.